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Anti Ds DNA Test Cost & Labs
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|Anti Ds DNA Antibody Test Price by ELISA Method||₹ 420|
|Anti Ds DNA Antibody Test Price by IFA Method||₹ 900|
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Frequently Asked Questions About Anti Ds DNA Antibody Test
What is Anti Ds DNA Antibody Test?
Double-Stranded DNA is the full form of anti Ds-DNA antibody test. Anti Ds DNA Antibody test is primarily done to diagnose lupus in a person whose autoimmune antibodies (ANA) test results is positive. The lupus is a condition that causes inflammation in organs such as kidney, heart, lung, etc.
Anti Ds DNA antibody can be done either in ELISA method or IFA method. Anti Ds DNA antibody belongs to the antinuclear antibodies which is produced by the immune system.
In this case, the white blood cells in our body mistakes double stranded DNA as a hazard and releases antibody to attack them. This condition where the immune system produces auto-antibodies against ds DNA is called lupus. Normally, the ANA test is performed first to know the cause of certain medical condition.
The anti Ds DNA test is done if the ANA test results are positive. This test may be ordered along with other auto-antibodies test such as anti-Sm (Smith antibody) for proper diagnosis. It is also done to monitor an ongoing treatment for lupus to determine the severity of the disease.
When is Ds-DNA Test Done?
Generally, the Ds-DNA test is done if you show signs and symptoms of having lupus and if the ANA test results are positive. The following are the symptoms of lupus
- Pain in muscle
- Weight loss
- Hair fall
- Inflammation or damage to organs or tissues
- Red rashes
It is also done to evaluate an ongoing treatment for lupus at regular intervals.
Is there any Preparation Required for Ds DNA Antibody Test?
The anti Ds-DNA antibody test is a simple blood test. There are no special preparations required for the test. You can have your normal diet and carry on your regular activities prior to the test.
It is important to consult with your doctor if you are taking any medications. It is also recommended to wear half sleeved cloth to the test for convenience.
What is the Procedure of Anti Ds DNA Antibody Test?
The procedure of anti ds DNA antibody test is similar to that of any other blood test. A tight elastic band will be tied around your arm to make the veins more visible. The area from where the blood is to be drawn will be cleaned with a disinfectant liquid.
A needle will be then injected into the vein to draw the blood which will be collected in a tube. After removing the needle, pressure will be applied on the punctured site using a cotton ball to stop the bleeding. The collected blood sample will be then sent to the laboratory for further testing.
This test can be done either by anti ds DNA antibody ELISA or anti ds DNA antibody IFA method.
What does the Anti Ds DNA Antibody Test Result Mean?
Normally the result of anti ds DNA antibody test is considered along with other auto-antibody tests. The normal range of auto-antibody present in the blood is between 30 IU/ml and 75 IU/ml. The high level of anti ds DNA antibody in the blood indicates that you may have lupus. The positive result of anti-Sm test and increased level of anti ds DNA antibody means that you definitely have lupus.
The low level of anti ds DNA antibody means that you may not have lupus. But this cannot be completely ruled out as about 50 percent of patients with lupus have very low level of anti ds DNA antibody in the blood.
The moderate level of anti Ds DNA antibody can be seen in Sjogren syndrome and mixed connective tissue disease (MCTD).
However if the ANA test result is negative there is no need for any other auto-antibody test as it indicates that the entire group is negative.