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Karyotyping Test Cost & Labs
View all the labs for chromosome/karyotype Tests and updated prices by clicking on the links as it may vary.
|Find Karyotype Test Labs, Cost & Book Appointment||Discounted Karyotyping test cost starting from|
|Karyotyping Test Price – Single||₹ 2,880|
|Karyotyping Test Price – Couple||₹ 3,400|
|POC / Chromosome Test Price|
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Frequently Asked Questions About Karyotyping Test
What is the Karyotyping test?
The karyotyping test helps to detect the abnormalities in a chromosome. The other name for Karyotyping is Chromosome Analysis. A chromosome is a thread-like structure containing DNA molecules. The human cell contains 46 chromosomes. The child will inherit 23 chromosomes each from their parents pairing each other. Abnormalities in the chromosome cause miscarriage.
The karyotype test helps to know the number of chromosomes present in the human cells. The chromosomes should be in the correct numbers and shapes. If there is an extra or missing chromosome then it might be a serious issue. Karyotyping helps to detect any kind of genetic disorder. It also helps in detecting genetic disorders.
What are the types of Karyotyping?
The most common types of Karyotyping done are Couple Karyotyping and POC Karyotyping. It helps to detect any chromosome abnormalities in parents and fetus.
1. Couple Karyotyping
The Couple Karyotyping is done on both the partners. The blood samples are used to detect chromosome abnormalities. This can also be done only on a single partner. If the test is done only on mother it is called Karyotyping Single.
2. Product of Conception (POC) Karyotyping
The Product of Conception is the full form of POC Karyotyping. It is done on the samples drawn from the fetus of a lost pregnancy. Your doctor may ask you to take POC Karyotyping on the fetus of lost pregnancy if he suspects any chromosome abnormalities. The chromosomal analysis is the other name for POC Karyotyping.
Who should take the Karyotyping Test?
The Karyotype test is highly recommended to those who had already suffered a pregnancy loss, recurrent miscarriages and undergoing assisted reproduction treatment. By taking the Karyotype Test you can avoid any possible miscarriage due to chromosome abnormalities.
If your doctor finds it appropriate, he may ask you to take the Karyotype Test in your early pregnancy to detect any chromosome abnormalities. In case of any chromosome abnormalities, your doctor may ask you to abort the child for your own benefit.
What is Chromosome Abnormality?
The human cell has 46 chromosomes which are inherited 23 each from their parents. These chromosomes pair with each other forming 23 pairs of chromosomes in the human cell.
The chromosomes should be in the correct number and shape. The missing or extra chromosome is chromosome abnormalities. If the shape of chromosomes changes, then it is also a chromosome abnormality.
What is the risk of abnormalities in chromosomes?
The abnormalities in chromosome affect the child born in various ways. The child may be born with the following medical conditions due to the abnormalities in chromosome
- Down Syndrome
- Digestive problems
- Heart defects
- Organ failure
- Disability in learning
- Poor growth
- Unusual features in baby
In addition to this, the abnormalities in the chromosome are the major cause of miscarriage. And an individual may develop congenital conditions during their lifetime. It is the root cause of various inherited diseases.
What are the different types of chromosome abnormalities?
The change in number or shape causes chromosome abnormalities. The different types of numerical and structural abnormalities are:
Abnormalities due to numerical changes
The human cells should contain 23 pairs of chromosomes. If there is a missing or extra chromosome, it is an abnormality. The most common numerical chromosome abnormalities are:
Aneuploid – It means that there is is a presence of an extra or missing chromosome in the human cells. The most common type of aneuploid is Down’s Syndrome and Turner’s Syndrome. In the case of Down’s Syndrome, there will be an extra pair of chromosome 21. The Down’s Syndrome is also called Trisomy 21. The children with Down’s Syndrome may have a small head, short neck, largemouth, small fingers, etc.
In Turner’s Syndrome, the X chromosome will be missing. It means that there will be only 45 chromosomes instead of 46 chromosomes.
Mosaicism – In the case of mosaicism, there will be two sets of the chromosome. The duplication commonly happens in sex chromosomes.
Abnormalities due to structural changes
The centromere present in the chromosome may be located in unusual region. The centromere is a region in which microtubes of the spindle attach. If the centromere is located in an unusual region, it will result in the unequal length of the arms.
Sometimes the chromosomes may detach and unite with some other chromosomes. This translocation increases the risk of chronic leukemia.
Is there any preparation required for Karyotype Test?
The Karyotyping Couple and Karyotyping Single are done with the blood samples. So there is no special preparation required for the test.
What do they look at Karyotyping Test?
The Karyotyping is done to examine the chromosomes in our body. The cells present in the blood carry chromosomes. So in Karyotype Test, they look for the numerical and structural change in chromosomes present in our blood.
What can I know from Karyotype Test?
The samples will be sent to the lab for a test. They look for the change in number, size & shape of chromosomes. The karyotype test shows abnormalities such as missing chromosome, extra chromosome, translocation of the chromosome, extra portions of the chromosome, etc.
Karyotype test helps to know the cause or possibility of miscarriage and genetic disorder in the baby. So it is advisable to take the Karyotype test in your early pregnancy.
What are the other types of Karyotyping done in India?
Other than the above-mentioned karyotype test there are different Karyotyping done with the samples of bone marrow, the fetus of a lost pregnancy, amniotic fluid, etc. The different types of Karyotyping are:
1. Bone Marrow Biopsy
In the case of bone marrow biopsy, the sample is taken from the bone marrow to look for chromosome disorders like leukemia, Down’s Syndrome, etc. It is also done in case of transplantation to match the patients and donors of bone marrow.
2. Chronic Villus Sampling
In case of Chronic Villus Sampling (CVS), a needle is used to remove the sample from the chronic villi. It is found within the placenta. The organ formed in the womb which nourishes the growth of child is called placenta. It is normally done between the 10th and 13th weeks of your pregnancy.
The amniotic fluid surrounding the baby is taken for the test. You can take the only test between the 15th and 20th weeks of your pregnancy. There are mild chances of miscarriage due to this method of drawing samples.