A breast cancer (BRCA) gene test is a blood or saliva test to check mutation in the gene responsible for controlling the normal growth of cells, namely BRCA1 and BRCA2. BRCA 1 test and BRCA 2 test together are done to detect mutation in the chromosomes.
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BRCA Test in India Through LabsAdvisor
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BRCA Testing Cost in India & Lab Details
Below is the list of cities providing BRCA testing cost in India, please click on the link of the specific city you want and you can see all the labs near you and book online.
You can also select the time slot suitable for you for your BRCA test. Click on the suitable link below to book any time of the day or night.
| BRCA Testing Cost in India | Price Starting From |
| BRCA Test Price in Delhi | ₹22950 |
| BRCA Test Price in Noida | ₹22950 |
| BRCA Test Price in Gurgaon | ₹21400 |
| BRCA Test Price in Bangalore | ₹24655 |
| BRCA Test Price in Mumbai | ₹24655 |
| BRCA Test Price in Chennai | ₹24655 |
| BRCA Test Price in Hyderabad | ₹24655 |
| BRCA Test Price in Other Indian Cities | ₹21400 |
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What is the BRCA Testing?
Genetic testing is a medical test that identifies the mutation (erratic change) in chromosomes, genes, or proteins. The outcome of the test can rule out or confirm a suspected genetic condition or determine the chances of a person developing or passing on a certain disease.
A breast cancer (BRCA) gene test is a blood or saliva test to check mutation in the gene responsible for controlling the normal growth of cells, namely BRCA1 and BRCA2. Finding mutations in these oncogenes can help in evaluating the risk of developing breast and ovarian cancer.
To know more about breast cancer refer here http://www.breastcancer.org
To know more about ovarian cancer refer here http://www.webmd.com/ovarian-cancer
What is the BRCA 1 Test and BRCA 2 Test?
BRCA1 and BRCA2 are tumor suppressor genes found in all humans. They produce proteins responsible for the repair of broken DNA. Some mutation (alterations) in these genes may cause the absence of the protein resulting in a lack of DNA repair process.
The cells with broken DNA can cause further mutations resulting in the uncontrollable growth of abnormal cells leading to cancer.
Researchers have identified more than 1800 of BRCA1 mutations. Not all mutations cause cancer. Some mutations are associated with an increased risk of breast cancer or ovarian cancer.
BRCA1 and BRCA2 mutations together account for 5-10% of all breast cancers. Breast and ovarian cancers due to BRCA1 and BRCA2 tend to develop at a younger age as compared to their non-hereditary counterparts.
A harmful BRCA1 or BRCA2 mutation can be inherited either from mother or father. A child has 50% chance of inheriting the faulty gene from his mutation-positive parent.
Harmful mutations of BRCA1 and BRCA2 may cause other types of cancers too in addition to breast and ovarian cancer. BRCA1 mutation may also cause fallopian tube cancer in women.
Men with BRCA2 mutations are at higher risk of breast cancer. Men and women with BRCA1 And BRCA2 may have an increased risk of pancreatic cancer. Risk of prostate cancer is also increased in men.
Why is a BRCA Test Done?
BRCA genetic testing is done to determine if there are any mutations in your DNA. This mutation will increase the risk of breast cancer.
It also increases the risk of cancers such as
- Ovarian cancer
- Prostate cancer
- Pancreatic cancer
- Melanoma
Your doctor will order the BRCA test in the following cases.
- A history of breast cancer diagnosed before 45 years of age.
- A history of having more than one cancer.
- Family history of breast cancer.
- A relative with BRCA mutation.
How is the BRCA Test Done?
Generally, the BRCA test is a simple blood test. A needle will be injected into the vein to draw the blood sample. After drawing enough blood samples, a cotton ball will be pressed against the puncture site to stop the bleeding.
The collected blood sample will be sent for DNA testing.
In some cases, the testing might be done with the saliva sample instead of the blood sample.
What are the Benefits of BRCA Testing?
Following are the benefits of genetic testing:
- It helps to identify people who are more prone to develop a medical condition that may be preventable. People with BRCA mutation and strong family history can opt for the removal of breasts and ovaries as a preventive measure.
- A true negative result provides a sense of relief regarding the future risk of cancer and takes away all the stress of frequent checkups, tests, and unnecessary preventive surgeries. Also if a person is found negative of BRCA mutation then his/her children will not inherit the family’s susceptibility to cancer.
What are the Limitations of BRCA Testing?
A serious drawback is difficulty in interpreting the result of the test. The test cannot ascertain if a person will develop symptoms of the disease.
- A person found positive of the mutation may never develop the disease. Scientists are of the opinion that environmental factors and/or other unknown mutations may be required to trigger the onset of the disease.
- Genetic testing is prone to provoke a considerable amount of anxiety especially when the asymptotic person is found positive. It may increase the level of stress and may strain relationships.
A genetic counselor plays a very important role in genetic testing. She will be working alongside the doctor and will engage in following
- She will provide details regarding the limitations and risks involved in taking the genetic test.
- Confirm the diagnosis of the disorder.
- Provide information regarding the disease, its present, and future implication.
- Will evaluate the risk of developing the disease and hence will advise the preventive treatment accordingly
- He will answer all the queries of the patient and provide psychological support to him and his family members.
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